diff --git a/tests/python/ui_simulate/modules/easy_keys.py b/tests/python/ui_simulate/modules/easy_keys.py
index 5060c57cd1c..df8ce69154d 100644
--- a/tests/python/ui_simulate/modules/easy_keys.py
+++ b/tests/python/ui_simulate/modules/easy_keys.py
@@ -354,7 +354,8 @@ def run(
     event_step.run_events = iter(event_iter)
     event_step._ticks = 0
 
-    bpy.app.timers.register(event_step, first_interval=0.0)
+    # Persistent so this keeps working when tests load a blend file.
+    bpy.app.timers.register(event_step, first_interval=0.0, persistent=True)
 
 
 def setup_default_preferences(preferences):